Product Datasheet  
Histone H4K20me3 Polyclonal Antibody  
Catalog Number: HW033  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Gene ID: 8290 Swiss Prot: Q16695
  • Form of Antibody:  
  • Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • Storage:  
  • Store at -20�?or -80�? Avoid freeze / thaw cycles.
  • Immunogen:  
  • A synthetic methylated peptide corresponding to residues surrounding K20 of human histone H4
  • reactivity:  
  • Hu Ms Rt
  • appl_detail:  
  • WB 1:500 - 1:2000

    IF 1:50 - 1:200
    IP 1:50 - 1:200

    CHIP 1:50 - 1:100

  • other_names:  
  • H4; H4/n; H4F2; H4FN; FO108; HIST2H4
  • Purification:  
  • Antibodies were produced by immunizing rabbits and were purified by antigen affinity-chromatography.
  • Specificity:  
  • Applications:  
  • WB IF IP ChIP
  • Background:  
  •  Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the centromeric copy.




 
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