Product Datasheet  
HSD17B12 Antibody  
Catalog Number: 36529  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: Q53GQ0
    NCBI Gene ID: 51144
    Gene Accssion: BC012043/Q53GQ0
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Fusion protein corresponding to a region derived from internal residues of human hydroxysteroid (17-beta) dehydrogenase 12
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:200-1:1000
    Immunohistochemistry: 1:50-1:200
  • other_names：  
  • KAR; SDR12C1
  • Purification：  
  • Antigen affinity purification.
  • Specificity：  
  • The antibody detects endogenous levels of total HSD17B12 protein.
  • Applications：  
  • WB IHC
  • Background：  
  • This gene encodes a very important 17beta-hydroxysteroid dehydrogenase (17beta-HSD) that converts estrone into estradiol in ovarian tissue. This enzyme is also involved in fatty acid elongation. Catalyzes the transformation of estrone (E1) into estradiol (E2), suggesting a central role in estrogen formation. Its strong expression in ovary and mammary gland suggest that it may constitute the major enzyme responsible for the conversion of E1 to E2 in women.



 
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