Product Datasheet
FASTKD3 Antibody
Catalog Number: 36471
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q14CZ7
NCBI Gene ID: 79072
Gene Accssion: BC113563
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to a region derived from internal residues of human FAST kinase domains 3
- appl_detail:
- Western blotting: 1:200-1:1000
- other_names:
- FAKD3;FAST kinase domains 3;FLJ23274
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total FASTKD3 protein.
- Background:
- This gene encodes a member of a small family of Fas-activated serine/threonine kinase domain (FASTKD) containing proteins that share an amino terminal mitochondrial targeting domain and multiple carboxy terminal FAST domains as well as a putative RNA-binding RAP domain. The members of this family are ubiquitously expressed and are generally most abundant in mitochondria-enriched tissues such as heart, skeletal muscle and brown-adipose tissue. Some members of this protein family may play a role in apoptosis. The protein encoded by this gene interacts with components of the mitochondrial respiratory and translation networks. A pseudogene of this gene is also present on chromosome 5. Alternative splicing results in multiple transcript variants.
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