Product Datasheet
CAPRIN1 Antibody
Catalog Number: 36227
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q14444
NCBI Gene ID: 4076
Gene Accssion: BC001731
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to residues near the C terminal of human cell cycle associated protein 1
- appl_detail:
- Western blotting: 1:200-1:1000
- other_names:
- M11S1; GPIAP1; RNG105; GPIP137; p137GPI
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total CAPRIN1 protein.
- Background:
- Caprin-1?is a?protein?that in humans is encoded by the?CAPRIN1?gene. May regulate the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation and migration in multiple cell types. May form homomultimers. Directly interacts with G3BP1 in cytoplasmic RNA granules. Binds directly and selectively to MYC and CCND2 RNAs. In neuronal cells, directly binds to several mRNAs associated with RNA granules, including BDNF, CAMK2A, CREB1, MAP2, NTRK2 mRNAs, as well as to GRIN1 and KPNB1 mRNAs, but not to rRNAs.
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