Product Datasheet
PIP5K1A Antibody
Catalog Number: 36206
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q99755
NCBI Gene ID: 8394
Gene Accssion: BC007833
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to residues near the C terminal of human phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
- appl_detail:
- Western blotting: 1:200-1:1000
Immunohistochemistry: 1:25-1:100
- other_names:
- PI51A;PIP5K1-alpha;PIP5KIalpha
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total PIP5K1A protein.
- Background:
- Phosphatidylinositol-4-phosphate 5-kinase type-1 alpha?is an?enzyme?that in humans is encoded by the?PIP5K1A?gene. Catalyzes the phosphorylation of phosphatidylinositol 4-phosphate (PtdIns4P) to form phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). PtdIns(4,5)P2 is involved in a variety of cellular processes and is the substrate to form phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3), another second messenger. The majority of PtdIns(4,5)P2 is thought to occur via type I phosphatidylinositol 4-phosphate 5-kinases given the abundance of PtdIns4P.
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