Product Datasheet
PFKL Antibody
Catalog Number: 36691
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P17858
NCBI Gene ID: 5211
Gene Accssion: BC008964/P17858
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to residues near the C terminal of human phosphofructokinase, liver
- appl_detail:
- Immunohistochemistry: 1:25-1:100
- other_names:
- PFK-B; PFK-L; ATP-PFK
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total PFKL protein.
- Background:
- This gene encodes the liver (L) subunit of an enzyme that catalyzes the conversion of D-fructose 6-phosphate to D-fructose 1,6-bisphosphate, which is a key step in glucose metabolism (glycolysis). This enzyme is a tetramer that may be composed of different subunits encoded by distinct genes in different tissues. Alternative splicing results in multiple transcript variants.
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