Product Datasheet
AGPS Antibody
Catalog Number: 36083
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: O00116
NCBI Gene ID: 8540
Gene Accssion: BC141820
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to residues near the C terminal of human alkylglycerone phosphate synthase
- appl_detail:
- Immunohistochemistry: 1:50-1:200
- other_names:
- ADAS; ADPS; ADAP-S; ADHAPS; ALDHPSY
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total AGPS protein.
- Background:
- This gene is a member of the FAD-binding oxidoreductase/transferase type 4 family. It encodes a protein that catalyzes the second step of ether lipid biosynthesis in which acyl-dihydroxyacetonephosphate (DHAP) is converted to alkyl-DHAP by the addition of a long chain alcohol and the removal of a long-chain acid anion. The protein is localized to the inner aspect of the peroxisomal membrane and requires FAD as a cofactor. Mutations in this gene have been associated with rhizomelic chondrodysplasia punctata, type 3 and Zellweger syndrome.
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