Product Datasheet
ALG2 Antibody
Catalog Number: 36082
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9H553
NCBI Gene ID: 85365
Gene Accssion: BC017876
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to residues near the C terminal of human ALG2, alpha-1,3/1,6-mannosyltransferase
- appl_detail:
- Immunohistochemistry: 1:25-1:100
- other_names:
- CDGIi; NET38; hALPG2
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total ALG2 protein.
- Background:
- This gene encodes a member of the glycosyltransferase 1 family. The encoded protein acts as an alpha 1,3 mannosyltransferase, mannosylating Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. Defects in this gene have been associated with congenital disorder of glycosylation type Ih (CDG-Ii). Alternative splicing results in multiple transcript variants.
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