Product Datasheet
AGA Antibody
Catalog Number: 36057
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P20933
NCBI Gene ID: 175
Gene Accssion: BC012392
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to a region derived from internal residues of human Aspartylglucosaminidase
- appl_detail:
- Western blotting: 1:200-1:1000
Immunohistochemistry: 1:15-1:50
- other_names:
- GA; AGU; ASRG
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total AGA protein.
- Background:
- Aspartylglucosaminidase is involved in the catabolism of N-linked oligosaccharides of glycoproteins. It cleaves asparagine from N-acetylglucosamines as one of the final steps in the lysosomal breakdown of glycoproteins. The lysosomal storage disease aspartylglycosaminuria is caused by a deficiency in the AGA enzyme. Alternatively spliced transcript variants have been identified.?
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