Product Datasheet  
b-Catenin(Phospho-Ser33) Antibody  
Catalog Number: 11218  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P35222
    NCBI Protein: NP_001091679.1
  • Form of Antibody：  
  • Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
  • Immunogen：  
  • Peptide sequence around phosphorylation site of serine 33 (L-D-S(p)-G-I) derived from Human b-Catenin.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • Predicted MW: 92kd
    Western blotting: 1:500~1:1000
    Immunohistochemistry: 1:50~1:100
  • other_names：  
  • CTNNB1; CATNB; CTNB1; CTNNB;
  • Purification：  
  • Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
  • Specificity：  
  • The antibody detects endogenous level of b-Catenin only when phosphorylated at serine 33.
  • Applications：  
  • WB IHC IF
  • Background：  
  • Involved in the regulation of cell adhesion and in signal transduction through the Wnt pathway.

    Novak A, et al. (1998) Proc Natl Acad Sci U S A; 95(8): 4374-4379
    Marin O, et al. (2003) Proc Natl Acad Sci U S A; 100(18): 10193-10200
    Okamura H, et al. (2004) Mol Cell Biol; 24(10): 4184-4195
    Xing Y, et al. (2003) Genes Dev; 17(22): 2753-2764
    Barth AI, et al. (1999) Proc Natl Acad Sci U S A; 96(9): 4947-4952



 
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