Product Datasheet  
MAP4K3 Antibody  
Catalog Number: 35951  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: Q8IVH8
    NCBI Gene ID: 8491
    Gene Accssion: BC071579
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Fusion protein corresponding to a region derived from internal residues of human Mitogen-activated protein kinase kinase kinase kinase 3
  • reactivity：  
  • Hu Ms
  • appl_detail：  
  • Western blotting: 1:500-1:2000
    Immunohistochemistry: 1:25-1:100
  • other_names：  
  • GLK; MEKKK3; MEKKK 3; MAPKKKK3; RAB8IPL1
  • Purification：  
  • Antigen affinity purification.
  • Specificity：  
  • The antibody detects endogenous levels of total MAP4K3 protein.
  • Applications：  
  • WB IHC
  • Background：  
  • This gene encodes a member of the mitogen-activated protein kinase kinase kinase kinase family. The encoded protein activates key effectors in cell signalling, among them c-Jun. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. Ubiquitously expressed in all tissues examined, with high levels in heart, brain, placenta, skeletal muscle, kidney and pancreas and lower levels in lung and liver.



 
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