Product Datasheet
PAX7 Antibody
Catalog Number: 35869
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P23759
NCBI Gene ID: 5081
Gene Accssion: BC121165
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to residues near the C terminal of human paired box 7
- appl_detail:
- Immunohistochemistry: 1:25-1:100
- other_names:
- HUP1; RMS2; PAX7B
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total PAX7 protein.
- Background:
- This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box 7 gene is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Three transcript variants encoding different isoforms have been found for this gene.
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