Product Datasheet
NTF3 Antibody
Catalog Number: 35845
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P20783
NCBI Gene ID: 4908
Gene Accssion: BC107075
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to a region derived from internal residues of human neurotrophin 3
- appl_detail:
- Western blotting: 1:200-1:1000
Immunohistochemistry: 1:15-1:50
- other_names:
- NT3; HDNF; NGF2; NGF-2
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total NTF3 protein.
- Background:
- The protein encoded by this gene is a member of the neurotrophin family, that controls survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NTF3-deficient mice generated by gene targeting display severe movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse.?
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