Product Datasheet
MAP3K14 Antibody
Catalog Number: 35838
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q99558
NCBI Gene ID: 9020
Gene Accssion: BC035576
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to residues near the C terminal of human mitogen-activated protein kinase kinase kinase 14
- appl_detail:
- Western blotting: 1:200-1:1000
Immunohistochemistry: 1:25-1:100
- other_names:
- HS; NIK; HSNIK; FTDCR1B
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total MAP3K14 protein.
- Background:
- This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor.
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