Product Datasheet
NEUROG3 Antibody
Catalog Number: 35837
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9Y4Z2
NCBI Gene ID: 50674
Gene Accssion: BC117488
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Full length fusion protein
- appl_detail:
- Western blotting: 1:200-1:1000
Immunohistochemistry: 1:25-1:100
- other_names:
- ngn3; Atoh5; NGN-3; Math4B; bHLHa7
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total NEUROG3 protein.
- Background:
- Neurogenin-3?is a?protein?that in humans is encoded by the?NEUROG3?gene. Neurogenin-3 is expressed in endocrine progenitor cells and is required for endocrine cell development in the pancreas and intestine.?It belongs to a family of basic helix-loop-helix (bHLH)?transcription factors?involved in the determination of neural precursor cells in the?neuroectoderm. The pancreas and brain the major splicing isoform does not code for a protein. Acts as a transcriptional regulator. Together with NKX2-2, initiates transcriptional activation of NEUROD1.
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