Product Datasheet
LGALS3 Antibody
Catalog Number: 35747
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P17931
NCBI Gene ID: 3958
Gene Accssion: BC001120
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Full length fusion protein
- appl_detail:
- Western blotting: 1:200-1:1000
Immunohistochemistry: 1:10-1:50
- other_names:
- L31; GAL3; MAC2; CBP35; GALBP; GALIG; LGALS2
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total LGALS3 protein.
- Background:
- This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. Alternate splicing results in multiple transcript variants.
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