Product Datasheet
TNFRSF12A Antibody
Catalog Number: 35709
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9NP84
NCBI Gene ID: 51330
Gene Accssion: BC002718
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to a region derived from internal residues of human Tumor necrosis factor receptor superfamily, member 12A
- appl_detail:
- Western blotting: 1:200-1:1000
Immunohistochemistry: 1:5-1:20
- other_names:
- FN14; CD266; TWEAKR
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total TNFRSF12A protein.
- Background:
- Tumor necrosis factor receptor superfamily member 12A?also known as the?Tweak-receptor?(TweakR) is aprotein?that in humans is encoded by the?TNFRSF12A?gene. Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins. Highly expressed in heart, placenta and kidney. Intermediate expression in lung, skeletal muscle and pancreas.
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