Product Datasheet
COL3A1 Antibody
Catalog Number: 35691
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P02461
NCBI Gene ID: 1281
Gene Accssion: BC028178
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to a region derived from internal residues of human collagen, type III, alpha 1
- appl_detail:
- Immunohistochemistry: 1:50-1:200
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total COL3A1 protein.
- Background:
- This gene encodes the pro-alpha1 chains of type III collagen, a fibrillar collagen that is found in extensible connective tissues such as skin, lung, uterus, intestine and the vascular system, frequently in association with type I collagen. Mutations in this gene are associated with Ehlers-Danlos syndrome types IV, and with aortic and arterial aneurysms. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.
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