Product Datasheet
ERBB4 Antibody
Catalog Number: 35681
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q15303
NCBI Gene ID: 2066
Gene Accssion: BC112199/Q15303
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to a region derived from internal residues of human v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4
- other_names:
- HER4; ALS19; p180erbB4
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total ERBB4 protein.
- Background:
This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation.?
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