Product Datasheet
BTG1 Antibody
Catalog Number: 35654
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P62324
NCBI Gene ID: 694
Gene Accssion: BC016759
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to a region derived from internal residues of human B-cell translocation gene 1, anti-proliferative
- appl_detail:
- Immunohistochemistry: 1:15-1:50
- other_names:
- B-cell translocation gene 1 protein; B-cell translocation gene 1; anti-proliferative; BTG1; Protein BTG1
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total BTG1 protein.
- Background:
- This gene is a member of an anti-proliferative gene family that regulates cell growth and differentiation. Expression of this gene is highest in the G0/G1 phases of the cell cycle and downregulated when cells progressed through G1. The encoded protein interacts with several nuclear receptors, and functions as a coactivator of cell differentiation. This locus has been shown to be involved in a t(8;12)(q24;q22) chromosomal translocation in a case of B-cell chronic lymphocytic leukemia.?
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