Product Datasheet
BMP3 Antibody
Catalog Number: 35653
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P12645
NCBI Gene ID: 651
Gene Accssion: BC096269
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to a region derived from internal residues of human bone morphogenetic protein 3
- appl_detail:
- Immunohistochemistry: 1:15-1:50
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total BMP3 protein.
- Background:
- BMP3 belongs to the transforming growth factor-beta (TGFB) superfamily. Bone morphogenic protein, also known as osteogenin, induces bone formation. Negatively regulates bone density. Antagonizes the ability of certain osteogenic BMPs to induce osteoprogenitor differentitation and ossification. Expressed in adult and fetal cartilage. Highly expressed in fracture tissue, particularly in osteoblasts, osteoclasts and chondroblasts.
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