Product Datasheet
ATP4B Antibody
Catalog Number: 35648
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P51164
NCBI Gene ID: 496
Gene Accssion: BC029059
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to a region derived from internal residues of human ATPase, H+/K+ exchanging, beta polypeptide
- appl_detail:
- Immunohistochemistry: 1:25-1:100
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total ATP4B protein.
- Background:
- The protein encoded by this gene belongs to a family of P-type cation-transporting ATPases. The gastric H+, K+-ATPase is a heterodimer consisting of a high molecular weight catalytic alpha subunit and a smaller but heavily glycosylated beta subunit. This enzyme is a proton pump that catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. It is also responsible for gastric acid secretion. This gene encodes the beta subunit of the gastric H+, K+-ATPase.
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