Product Datasheet
RAP1A Antibody
Catalog Number: 35640
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P62834
NCBI Gene ID: 5906
Gene Accssion: BC014086
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Full length fusion protein
- appl_detail:
- Immunohistochemistry: 1:25-1:100
- other_names:
- RAP1; KREV1; KREV-1; SMGP21
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total RAP1A protein.
- Background:
- The product of this gene belongs to the family of RAS-related proteins. These proteins share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between RAP proteins and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. The product of this gene counteracts the mitogenic function of RAS because it can interact with RAS GAPs and RAF in a competitive manner. Two transcript variants encoding the same protein have been identified for this gene.?
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