Product Datasheet
CALCR Antibody
Catalog Number: 35633
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P30988
NCBI Gene ID: 799
Gene Accssion: BC069611
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to a region derived from internal residues of human calcitonin receptor
- appl_detail:
- Immunohistochemistry: 1:25-1:100
- other_names:
- CRT; CTR; CT-R; CTR1
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total CALCR protein.
- Background:
- This gene encodes a high affinity receptor for the peptide hormone calcitonin and belongs to a subfamily of seven transmembrane-spanning G protein-coupled receptors. The encoded protein is involved in maintaining calcium homeostasis and in regulating osteoclast-mediated bone resorption. Polymorphisms in this gene have been associated with variations in bone mineral density and onset of osteoporosis. Alternate splicing results in multiple transcript variants.
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