Product Datasheet
APLNR Antibody
Catalog Number: 35623
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P35414
NCBI Gene ID: 187
Gene Accssion: BC032688
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to a region derived from internal residues of human apelin receptor
- appl_detail:
- Western blotting: 1:200-1:1000
Immunohistochemistry: 1:15-1:50
- other_names:
- APJ; APJR; HG11; AGTRL1
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total APLNR protein.
- Background:
- This gene encodes a member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor, but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. It functions in the cardiovascular and central nervous systems, in glucose metabolism, in embryonic and tumor angiogenesis and as a human immunodeficiency virus (HIV-1) coreceptor. Two transcript variants resulting from alternative splicing have been identified.?
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