Product Datasheet
IL31RA Antibody
Catalog Number: 35609
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q8NI17
NCBI Gene ID: 133396
Gene Accssion: BC110490
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to a region derived from internal residues of human Interleukin-31 receptor subunit alpha
- appl_detail:
- Immunohistochemistry: 1:25-1:100
- other_names:
- CRL; GPL; CRL3; GLMR; GLM-R; PLCA2; hGLM-R; IL-31RA
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total IL31RA protein.
- Background:
- The protein encoded by this gene belongs to the type I cytokine receptor family. This receptor, with homology to gp130, is expressed on monocytes, and is involved in IL-31 signaling via activation of STAT-3 and STAT-5. It functions either as a monomer, or as part of a receptor complex with oncostatin M receptor (OSMR). Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
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