Product Datasheet
COX8A Antibody
Catalog Number: 35584
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P10176
NCBI Gene ID: 1351
Gene Accssion: BC063025
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to a region derived from internal residues of human cytochrome c oxidase subunit VIIIA (ubiquitous)
- appl_detail:
- Immunohistochemistry: 1:10-1:50
- other_names:
- COX; COX8; VIII; COX8L; COX8-2; VIII-L
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total COX8A protein.
- Background:
- The protein encoded by this gene is the terminal enzyme of the respiratory chain, coupling the transfer of electrons from cytochrome c to molecular oxygen, with the concomitant production of a proton electrochemical gradient across the inner mitochondrial membrane. In addition to 3 mitochondrially encoded subunits, which perform the catalytic function, the eukaryotic enzyme contains nuclear-encoded smaller subunits, ranging in number from 4 in some organisms to 10 in mammals. It has been proposed that nuclear-encoded subunits may be involved in the modulation of the catalytic function. This gene encodes one of the nuclear-encoded subunits.
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