Product Datasheet
APOA1 Antibody
Catalog Number: 35570
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P02647
NCBI Gene ID: 335
Gene Accssion: BC005380
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to a region derived from internal residues of human apolipoprotein A-I
- appl_detail:
- Immunohistochemistry: 1:25-1:100
- other_names:
- Apo-AI; ApoA-I; APOA1; Apolipoprotein A-I;
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total APOA1 protein.
- Background:
- This gene encodes apolipoprotein A-I, which is the major protein component of high density lipoprotein (HDL) in plasma. The protein promotes cholesterol efflux from tissues to the liver for excretion, and it is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. This gene is closely linked with two other apolipoprotein genes on chromosome 11. Defects in this gene are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis.
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