Product Datasheet
MAT1A Antibody
Catalog Number: 35551
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q00266
NCBI Gene ID: 4143
Gene Accssion: BC018359
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to a region derived from internal residues of human methionine adenosyltransferase I, alpha
- appl_detail:
- Western blotting: 1:500-1:2000
- other_names:
- MAT; SAMS; MATA1; SAMS1
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total MAT1A protein.
- Background:
- This gene catalyzes a two-step reaction that involves the transfer of the adenosyl moiety of ATP to methionine to form S-adenosylmethionine and tripolyphosphate, which is subsequently cleaved to PPi and Pi. S-adenosylmethionine is the source of methyl groups for most biological methylations. The encoded protein is found as a homotetramer (MAT I) or a homodimer (MAT III) whereas a third form, MAT II (gamma), is encoded by the MAT2A gene. Mutations in this gene are associated with methionine adenosyltransferase deficiency.
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