Product Datasheet
TUBB3 Antibody
Catalog Number: 35539
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q13509
NCBI Gene ID: 10381
Gene Accssion: BC000748
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to a region derived from internal residues of human Tubulin beta-3 chain
- appl_detail:
- Western blotting: 1:500-1:1000
Immunohistochemistry: 1:25-1:50
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total TUBB3 protein.
- Background:
- his gene encodes a class III member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is primarily expressed in neurons and may be involved in neurogenesis and axon guidance and maintenance. Mutations in this gene are the cause of congenital fibrosis of the extraocular muscles type 3. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 6
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