Product Datasheet
ACE2 Antibody
Catalog Number: 35524
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q9BYF1;
NCBI Gene#:59272
- Form of Antibody:
- Rabbit IgG in 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
- Immunogen:
- Recombinant fragment corresponding to a region within amino acids 406 and 677 of ACE2.
- appl_detail:
- Western blotting: 1:500-1:3000
- other_names:
- ACEH antibody; DKFZp434A014 antibody; ACE2 antibody; metalloprotease MPROT15 antibody; angiotensin-converting enzyme homolog antibody; angiotensin I converting enzyme 2 antibody; ACE-related carboxypeptidase antibody; angiotensin-converting enzyme 2 antib
- Purification:
- Antibodies were purified by antigen-affinity chromatography.
- Specificity:
- The antibody detects endogenous levels of total ACE2 protein.
- Background:
- The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63. [provided by RefSeq]
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