Product Datasheet  
MLH1 Antibody  
Catalog Number: 35518  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:P40692;
    NCBI Gene#:4292
  • Form of Antibody：  
  • Rabbit IgG in 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Recombinant fragment corresponding to a region within amino acids 8 and 297 of MLH1.
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:500-1:3000
  • other_names：  
  • COCA2 antibody; FCC2 antibody; HNPCC antibody; HNPCC2 antibody; MGC5172 antibody; hMLH1 antibody; MLH1 antibody; DNA mismatch repair protein Mlh1 antibody; mutL protein homolog 1 antibody; "mutL homolog 1; colon cancer; nonpolyposis type 2 (E. coli) antib
  • Purification：  
  • Antibodies were purified by antigen-affinity chromatography.
  • Specificity：  
  • The antibody detects endogenous levels of total MLH1 protein.
  • Applications：  
  • WB
  • Background：  
  • This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Alternatively spliced transcript variants encoding different isoforms have been described, but their full-length natures have not been determined. [provided by RefSeq]



 
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