Product Datasheet
HDAC1 Antibody
Catalog Number: 35517
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q13547;
NCBI Gene#:3065
- Form of Antibody:
- Rabbit IgG in 1XPBS, 1%BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
- Immunogen:
- Recombinant fragment corresponding to a region within amino acids 11 and 313 of HDAC1.
- appl_detail:
- Western blotting: 1:500-1:3000
- other_names:
- DKFZp686H12203 antibody; GON-10 antibody; HD1 antibody; RPD3 antibody; RPD3L1 antibody; HDAC1 antibody; histone deacetylase 1 antibody; "reduced potassium dependency; yeast homolog-like 1 antibody"
- Purification:
- Antibodies were purified by antigen-affinity chromatography.
- Specificity:
- The antibody detects endogenous levels of total HDAC1 protein.
- Background:
- Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. [provided by RefSeq]
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