Product Datasheet
Glucagon Antibody
Catalog Number: 35510
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P01275;
NCBI Gene#:2641
- Form of Antibody:
- Rabbit IgG in 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
- Immunogen:
- Recombinant fragment corresponding to a region within amino acids 1 and 180 of Glucagon.
- appl_detail:
- Western blotting: 1:500-1:3000
- other_names:
- GLP1 antibody; GLP2 antibody; GRPP antibody; GCG antibody; glicentin-related polypeptide antibody; glucagon antibody; glucagon-like peptide 2 antibody; glucagon-like peptide 1 antibody
- Purification:
- Antibodies were purified by antigen-affinity chromatography.
- Specificity:
- The antibody detects endogenous levels of total Glucagon protein.
- Background:
- The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon. [provided by RefSeq]
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