Product Datasheet  
Troponin I (cardiac) Antibody  
Catalog Number: 35508  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:P19429;
    NCBI Gene#:7137
  • Form of Antibody：  
  • Rabbit IgG in 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Recombinant fragment corresponding to a region within amino acids 1 and 210 of Troponin I .
  • reactivity：  
  • Hu Ms
  • appl_detail：  
  • Western blotting: 1:1000-1:10000
  • other_names：  
  • CMD1FF antibody; CMD2A antibody; CMH7 antibody; MGC116817 antibody; RCM1 antibody; TNNC1 antibody; cTnI antibody; TNNI3 antibody; "troponin I; cardiac muscle antibody"; troponin I type 3 (cardiac) antibody
  • Purification：  
  • Antibodies were purified by antigen-affinity chromatography.
  • Specificity：  
  • The antibody detects endogenous levels of total Troponin I (cardiac) protein.
  • Applications：  
  • WB
  • Background：  
  • Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq]



 
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