Product Datasheet
BNIP3 Antibody
Catalog Number: 35500
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q12983;
NCBI Gene#:664
- Form of Antibody:
- Rabbit IgG in 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
- Immunogen:
- Synthetic peptide corresponding to a region within amino acids 14 and 108 of BNIP3.
- appl_detail:
- Western blotting: 1:500-1:3000
- other_names:
- NIP3 antibody; BNIP3 antibody; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 antibody; BCL2/adenovirus E1B 19kDa interacting protein 3 antibody
- Purification:
- Antibodies were purified by antigen-affinity chromatography.
- Specificity:
- The antibody detects endogenous levels of total BNIP3 protein.
- Background:
- This gene is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein which is responsible for the protection of virally-induced cell death, as well as E1B 19 kDa-like sequences of BCL2, also an apoptotic protector. This gene contains a BH3 domain and a transmembrane domain, which have been associated with pro-apoptotic function. The dimeric mitochondrial protein encoded by this gene is known to induce apoptosis, even in the presence of BCL2. [provided by RefSeq]
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