Product Datasheet
CD55 Antibody
Catalog Number: 35495
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P08174;
NCBI Gene#:1604
- Form of Antibody:
- Rabbit IgG in 1XPBS, 1%BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
- Immunogen:
- Recombinant fragment corresponding to a region within amino acids 121 and 381 of CD55.
- appl_detail:
- Western blotting: 1:500-1:3000
- other_names:
- CR antibody; CROM antibody; DAF antibody; TC antibody; CD55 antibody; CD55 antigen antibody; decay accelerating factor for complement antibody; complement decay-accelerating factor antibody; "CD55 molecule; decay accelerating factor for complement (Cromer
- Purification:
- Antibodies were purified by antigen-affinity chromatography.
- Specificity:
- The antibody detects endogenous levels of total CD55 protein.
- Background:
- This gene encodes a protein involved in the regulation of the complement cascade. The encoded glycoprotein is also known as the decay-accelerating factor (DAF); binding of DAF to complement proteins accelerates their decay, disrupting the cascade and preventing damage to host cells. Antigens present on the DAF glycoprotein constitute the Cromer blood group system (CROM). Two alternatively spliced transcripts encoding different proteins have been identified. The predominant transcript encodes a membrane-bound protein expressed on cells exposed to plasma component proteins but an alternatively spliced transcript produces a soluble protein present at much lower levels. Additional, alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq]
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