Product Datasheet
IRAK Antibody
Catalog Number: 35487
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P51617;
NCBI Gene#:3654
- Form of Antibody:
- Rabbit IgG in 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
- Immunogen:
- Recombinant fragment corresponding to a region within amino acids 185 and 429 of IRAK.
- appl_detail:
- Western blotting: 1:500-1:3000
- other_names:
- IRAK antibody; pelle antibody; IRAK1 antibody; interleukin-1 receptor-associated kinase 1 antibody; Pelle homolog antibody; IRAK-1 antibody
- Purification:
- Antibodies were purified by antigen-affinity chromatography.
- Specificity:
- The antibody detects endogenous levels of total IRAK protein.
- Background:
- This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
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