Product Datasheet
Estrogen Receptor beta Antibody
Catalog Number: 35475
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q92731;
NCBI Gene#:2100
- Form of Antibody:
- Rabbit IgG in 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
- Immunogen:
- Recombinant fragment corresponding to a region within amino acids 113 and 400 of Estrogen Receptor beta.
- appl_detail:
- Western blotting: 1:500-1:3000
- other_names:
- ER-BETA antibody; ESR-BETA antibody; ESRB antibody; ESTRB antibody; Erb antibody; NR3A2 antibody; ESR2 antibody; estrogen nuclear receptor beta variant a antibody; estrogen nuclear receptor beta variant b antibody; estrogen receptor beta antibody; estroge
- Purification:
- Antibodies were purified by antigen-affinity chromatography.
- Specificity:
- The antibody detects endogenous levels of total Estrogen Receptor beta protein.
- Background:
- This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized. [provided by RefSeq]
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