Product Datasheet  
NF-H Antibody  
Catalog Number: 35469  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:P12036;
    NCBI Gene#:4744
  • Form of Antibody：  
  • Rabbit IgG in 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Recombinant protein fragment contain a sequence corresponding to a region within amino acids 380 and 629 of Human 200 kD Neurofilament Heavy.
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:500-1:3000
  • other_names：  
  • NFH antibody; NEFH antibody; NF-H antibody; neurofilament heavy polypeptide antibody; "neurofilament; heavy polypeptide 200kDa antibody"; 200 kDa neurofilament protein antibody; neurofilament triplet H protein antibody; "neurofilament; heavy polypeptide a
  • Purification：  
  • Antibodies were purified by antigen-affinity chromatography.
  • Specificity：  
  • The antibody detects endogenous levels of total NF-H protein.
  • Applications：  
  • WB
  • Background：  
  • Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. [provided by RefSeq]



 
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