Product Datasheet
NMDAR2B Antibody
Catalog Number: 35467
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q13224;
NCBI Gene#:2904
- Form of Antibody:
- Rabbit IgG in 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
- Immunogen:
- Recombinant fragment corresponding to a region within amino acids 1010 and 1289 of NMDAR2B.
- appl_detail:
- Western blotting: 1:500-1:3000
- other_names:
- MGC142178 antibody; MGC142180 antibody; NMDAR2B antibody; NR2B antibody; hNR3 antibody; GRIN2B antibody; glutamate receptor subunit epsilon-2 antibody; N-methyl-D-aspartate receptor subunit 3 antibody; glutamate [NMDA] receptor subunit epsilon-2 antibody;
- Purification:
- Antibodies were purified by antigen-affinity chromatography.
- Specificity:
- The antibody detects endogenous levels of total NMDAR2B protein.
- Background:
- N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of three different subunits: NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The NR2 subunit acts as the agonist binding site for glutamate. This receptor is the predominant excitatory neurotransmitter receptor in the mammalian brain. [provided by RefSeq]
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