Product Datasheet  
PKC theta Antibody  
Catalog Number: 35465  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#:Q04759;
    NCBI Gene#:5588
  • Form of Antibody:  
  • Rabbit IgG in 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Recombinant fragment corresponding to a region within amino acids 1 and 273 of PKC theta.
  • reactivity:  
  • Hu
  • appl_detail:  
  • Western blotting: 1:1000-1:10000
  • other_names:  
  • MGC126514 antibody; MGC141919 antibody; PRKCT antibody; nPKC-theta antibody; PRKCQ antibody; protein kinase C theta type antibody; "protein kinase C; theta antibody"
  • Purification:  
  • Antibodies were purified by antigen-affinity chromatography.
  • Specificity:  
  • The antibody detects endogenous levels of total PKC theta protein.
  • Applications:  
  • WB
  • Background:  
  • Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipid-dependent protein kinase. This kinase is important for T-cell activation. It is required for the activation of the transcription factors NF-kappaB and AP-1, and may link the T cell receptor (TCR) signaling complex to the activation of the transcription factors. [provided by RefSeq]



 
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