Product Datasheet
ANGPTL3 Antibody
Catalog Number: 35462
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q9Y5C1;
NCBI Gene#:27329
- Form of Antibody:
- Rabbit IgG in 1XPBS, 1%BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
- Immunogen:
- Recombinant fragment corresponding to a region within amino acids 104 and 460 of ANGPTL3.
- appl_detail:
- Western blotting: 1:500-1:3000
- other_names:
- ANGPT5 antibody; FHBL2 antibody; ANGPTL3 antibody; ANG-5 antibody; angiopoietin-related protein 3 antibody; angiopoietin 5 antibody; angiopoietin-like 3 antibody
- Purification:
- Antibodies were purified by antigen-affinity chromatography.
- Specificity:
- The antibody detects endogenous levels of total ANGPTL3 protein.
- Background:
- The protein encoded by this gene is a member of the angiopoietin-like family of secreted factors. It is predominantly expressed in the liver, and has the characteristic structure of angiopoietins, consisting of a signal peptide, N-terminal coiled-coil domain and the C-terminal fibrinogen (FBN)-like domain. The FBN-like domain in angiopoietin-like 3 protein was shown to bind alpha-5/beta-3 integrins, and this binding induced endothelial cell adhesion and migration. This protein may also play a role in the regulation of angiogenesis. [provided by RefSeq]
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