Product Datasheet
MMP19 Antibody
Catalog Number: 35461
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q99542;
NCBI Gene#:4327
- Form of Antibody:
- Rabbit IgG in 1XPBS, 1%BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
- Immunogen:
- Recombinant fragment corresponding to a region within amino acids 210 and 508 of MMP19.
- appl_detail:
- Western blotting: 1:500-1:3000
- other_names:
- MMP18 antibody; RASI-1 antibody; MMP19 antibody; MMP-19 antibody; matrix metalloproteinase 18 antibody; matrix metalloproteinase RASI antibody; matrix metalloproteinase-19 antibody; MMP-18 antibody; matrix metalloproteinase 19 antibody; matrix metalloprot
- Purification:
- Antibodies were purified by antigen-affinity chromatography.
- Specificity:
- The antibody detects endogenous levels of total MMP19 protein.
- Background:
- Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This protein is expressed in human epidermis and it has a role in cellular proliferation as well as migration and adhesion to type I collagen. Multiple transcript variants encoding distict isoforms have been identified for this gene. [provided by RefSeq]
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