Product Datasheet
BMF Antibody
Catalog Number: 35459
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q96LC9;
NCBI Gene#:90427
- Form of Antibody:
- Rabbit IgG in 1XPBS, 1%BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
- Immunogen:
- Recombinant fragment corresponding to a region within amino acids 1 and 184 of BMF.
- appl_detail:
- Western blotting: 1:500-1:3000
- other_names:
- FLJ00065 antibody; BMF antibody; bcl-2-modifying factor antibody; Bcl2 modifying factor antibody
- Purification:
- Antibodies were purified by antigen-affinity chromatography.
- Specificity:
- The antibody detects endogenous levels of total BMF protein.
- Background:
- The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a single BCL2 homology domain 3 (BH3), and has been shown to bind BCL2 proteins and function as an apoptotic activator. This protein is found to be sequestered to myosin V motors by its association with dynein light chain 2, which may be important for sensing intracellular damage and triggering apoptosis. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]
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