Product Datasheet
CKII alpha Antibody
Catalog Number: 35452
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P68400;
NCBI Gene#:1457
- Form of Antibody:
- Rabbit IgG in 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
- Immunogen:
- Recombinant fragment contain a sequence corresponding to a region within amino acids 166 and 360 of Casein Kinase 2 alpha.
- appl_detail:
- Western blotting: 1:500-1:3000
- other_names:
- CK2A1 antibody; CKII antibody; CSNK2A1 antibody; casein kinase II alpha 1 subunit antibody; CK II alpha antibody; protein kinase CK2 antibody; CK2 catalytic subunit alpha antibody; casein kinase II subunit alpha antibody; "casein kinase 2; alpha 1 polypep
- Purification:
- Antibodies were purified by antigen-affinity chromatography.
- Specificity:
- The antibody detects endogenous levels of total CKII alpha protein.
- Background:
- Casein kinase II is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. The kinase exists as a tetramer and is composed of an alpha, an alpha-prime, and two beta subunits. The alpha subunits contain the catalytic activity while the beta subunits undergo autophosphorylation. The protein encoded by this gene represents the alpha subunit. While this gene is found on chromosome 20, a related transcribed pseudogene is found on chromosome 11. Three transcript variants encoding two different proteins have been found for this gene. [provided by RefSeq]
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