Product Datasheet  
PDGF Receptor alpha Antibody  
Catalog Number: 35451  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#:P16234;
    NCBI Gene#:5156
  • Form of Antibody:  
  • Rabbit IgG in 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Recombinant fragment contain a sequence corresponding to a region within amino acids 331 and 709 of PDGF Receptor alpha.
  • reactivity:  
  • Hu Ms
  • appl_detail:  
  • Western blotting: 1:500-1:3000
  • other_names:  
  • CD140A antibody; MGC74795 antibody; PDGFR2 antibody; RHEPDGFRA antibody; PDGFRA antibody; CD140 antigen-like family member A antibody; CD140a antigen antibody; PDGF-R-alpha antibody; rearranged-in-hypereosinophilia-platelet derived growth factor receptor
  • Purification:  
  • Antibodies were purified by antigen-affinity chromatography.
  • Specificity:  
  • The antibody detects endogenous levels of total PDGF Receptor alpha protein.
  • Applications:  
  • WB
  • Background:  
  • This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes. [provided by RefSeq]



 
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