Product Datasheet
PDGF Receptor alpha Antibody
Catalog Number: 35451
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P16234;
NCBI Gene#:5156
- Form of Antibody:
- Rabbit IgG in 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
- Immunogen:
- Recombinant fragment contain a sequence corresponding to a region within amino acids 331 and 709 of PDGF Receptor alpha.
- appl_detail:
- Western blotting: 1:500-1:3000
- other_names:
- CD140A antibody; MGC74795 antibody; PDGFR2 antibody; RHEPDGFRA antibody; PDGFRA antibody; CD140 antigen-like family member A antibody; CD140a antigen antibody; PDGF-R-alpha antibody; rearranged-in-hypereosinophilia-platelet derived growth factor receptor
- Purification:
- Antibodies were purified by antigen-affinity chromatography.
- Specificity:
- The antibody detects endogenous levels of total PDGF Receptor alpha protein.
- Background:
- This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes. [provided by RefSeq]
© Signalway Biotechnology All Rights Reserved.