Product Datasheet  
TIE2 Antibody  
Catalog Number: 35450  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:Q02763 ;
    NCBI Gene#:7010
  • Form of Antibody：  
  • Rabbit IgG in 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Recombinant protein fragment contain a sequence corresponding to a region within amino acids 779 and 1102 of TIE2.
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:500-1:3000
  • other_names：  
  • CD202B antibody; TIE-2 antibody; TIE2 antibody; VMCM antibody; VMCM1 antibody; TEK antibody; p140 TEK antibody; hTIE2 antibody; tyrosine-protein kinase receptor TIE-2 antibody; tyrosine-protein kinase receptor TEK antibody; soluble TIE2 variant 1 antibody
  • Purification：  
  • Antibodies were purified by antigen-affinity chromatography.
  • Specificity：  
  • The antibody detects endogenous levels of total TIE2 protein.
  • Applications：  
  • WB
  • Background：  
  • The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations; the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase. [provided by RefSeq]



 
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