Product Datasheet  
STAT6(Phospho-Thr645) Antibody  
Catalog Number: 11051  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P42226
    NCBI Protein: NP_003144.3
  • Form of Antibody：  
  • Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
  • Immunogen：  
  • Peptide sequence around phosphorylation site of threonine 645 (P-A-T(p)-I-K) derived from Human STAT6.
  • reactivity：  
  • Hu
  • appl_detail：  

  • Predicted MW: 110kd
    Immunohistochemistry: 1:50~1:100

  • other_names：  
  • IL-4-STAT; STAT6B; STAT6C
  • Purification：  
  • Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
  • Specificity：  
  • The antibody detects endogenous level of STAT6 only when phosphorylated at threonine 645.
  • Applications：  
  • WB IHC
  • Background：  

  • Carries out a dual function: signal transduction and activation of transcription. Involved in interleukin-4 signalling.

    Nelms K, et al. (1999) Annu Rev Immunol. 17:701-738.
    Malabarba M G, et al. (1996) Biochem. J. 319:865-872.
    Hou J, et al. (1994) Science. 265:1701-1706.
    Quelle F W, et al. (1995) Mol Cell Biol. 15: 3336-3343.
    Takeda K, et al. (1996) Nature. 380: 627-630.




 
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