Product Datasheet  
Pyruvate Kinase (liver/RBC) Antibody  
Catalog Number: 35442  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:P30613;
    NCBI Gene#:5313
  • Form of Antibody：  
  • Rabbit IgG in 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Recombinant fragment corresponding to a region within amino acids 1 and 301 of Pyruvate Kinase .
  • reactivity：  
  • Hu Rt Ms
  • appl_detail：  
  • Western blotting: 1:500-1:20000
  • other_names：  
  • PK1 antibody; PKL antibody; PKR antibody; PKRL antibody; RPK antibody; PKLR antibody; R-type/L-type pyruvate kinase antibody; pyruvate kinase type L antibody; red cell/liver pyruvate kinase antibody; pyruvate kinase 1 antibody; pyruvate kinase isozyme R/L
  • Purification：  
  • Antibodies were purified by antigen-affinity chromatography.
  • Specificity：  
  • The antibody detects endogenous levels of total Pyruvate Kinase (liver/RBC) protein.
  • Applications：  
  • WB
  • Background：  
  • The protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]



 
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